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Histone deacetylase inhibitors vorinostat and panobinostat induce G1 cell cycle arrest and apoptosis in multidrug resistant sarcoma cell lines
Synovial sarcoma and high grade chondrosarcoma are characterized by their lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing...
Autores principales: | Bernhart, Eva, Stuendl, Nicole, Kaltenegger, Heike, Windpassinger, Christian, Donohue, Nicholas, Leithner, Andreas, Lohberger, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652778/ https://www.ncbi.nlm.nih.gov/pubmed/29100385 http://dx.doi.org/10.18632/oncotarget.20460 |
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