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Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A

Myelodysplastic syndromes (MDS) are a diverse group of malignant clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, dysplastic cell morphology in one or more hematopoietic lineages, and a risk of progression to acute myeloid leukemia (AML). Approximately 50% of MDS...

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Detalles Bibliográficos
Autores principales: Oben, Karine Z., Alhakeem, Sara S., McKenna, Mary K., Brandon, Jason A., Mani, Rajeswaran, Noothi, Sunil K., Jinpeng, Liu, Akunuru, Shailaja, Dhar, Sanjit K., Singh, Inder P., Liang, Ying, Wang, Chi, Abdel-Latif, Ahmed, Stills Jr, Harold F., St. Clair, Daret K., Geiger, Hartmut, Muthusamy, Natarajan, Tohyama, Kaoru, Gupta, Ramesh C., Bondada, Subbarao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652791/
https://www.ncbi.nlm.nih.gov/pubmed/29100399
http://dx.doi.org/10.18632/oncotarget.20497