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Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A
Myelodysplastic syndromes (MDS) are a diverse group of malignant clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, dysplastic cell morphology in one or more hematopoietic lineages, and a risk of progression to acute myeloid leukemia (AML). Approximately 50% of MDS...
Autores principales: | Oben, Karine Z., Alhakeem, Sara S., McKenna, Mary K., Brandon, Jason A., Mani, Rajeswaran, Noothi, Sunil K., Jinpeng, Liu, Akunuru, Shailaja, Dhar, Sanjit K., Singh, Inder P., Liang, Ying, Wang, Chi, Abdel-Latif, Ahmed, Stills Jr, Harold F., St. Clair, Daret K., Geiger, Hartmut, Muthusamy, Natarajan, Tohyama, Kaoru, Gupta, Ramesh C., Bondada, Subbarao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652791/ https://www.ncbi.nlm.nih.gov/pubmed/29100399 http://dx.doi.org/10.18632/oncotarget.20497 |
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