TERT promoter status and gene copy number gains: effect on TERT expression and association with prognosis in breast cancer

Upregulation of the telomerase reverse transcriptase (TERT) gene in human cancers leads to telomerase activation, which contributes to the growth advantage and survival of tumor cells. Molecular mechanisms of TERT upregulation are complex, tumor-specific and can be clinically relevant. To investigat...

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Detalles Bibliográficos
Autores principales: Gay-Bellile, Mathilde, Véronèse, Lauren, Combes, Patricia, Eymard-Pierre, Eleonore, Kwiatkowski, Fabrice, Dauplat, Marie-Mélanie, Cayre, Anne, Privat, Maud, Abrial, Catherine, Bignon, Yves-Jean, Mouret-Reynier, Marie-Ange, Vago, Philippe, Penault-Llorca, Frédérique, Tchirkov, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652798/
https://www.ncbi.nlm.nih.gov/pubmed/29100407
http://dx.doi.org/10.18632/oncotarget.20560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652798/
https://www.ncbi.nlm.nih.gov/pubmed/29100407
http://dx.doi.org/10.18632/oncotarget.20560

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