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The ROS/NF-κB/NR4A2 pathway is involved in H(2)O(2) induced apoptosis of resident cardiac stem cells via autophagy

Cardiac stem cells (CSCs)-based therapy provides a promising avenue for the management of ischemic heart diseases. However, engrafted CSCs are subjected to acute cell apoptosis in the ischemic microenvironment. Here, stem cell antigen 1 positive (Sca-1(+)) CSCs proved to own therapy potential were c...

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Detalles Bibliográficos
Autores principales: Shi, Xingxing, Li, Wenjing, Liu, Honghong, Yin, Deling, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652805/
https://www.ncbi.nlm.nih.gov/pubmed/29100414
http://dx.doi.org/10.18632/oncotarget.20747