Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity

Autophagy is a cellular bulk degradation pathway implicated in various diseases. Inhibition of autophagy has been regarded as a new therapeutic strategy for cancer treatment, especially in combination with chemotherapy. In our study, we identified two natural compounds, dauricine (DAC) and daurisoli...

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Detalles Bibliográficos
Autores principales: Wu, Ming-Yue, Wang, Sheng-Fang, Cai, Cui-Zan, Tan, Jie-Qiong, Li, Min, Lu, Jin-Jian, Chen, Xiu-Ping, Wang, Yi-Tao, Zheng, Wei, Lu, Jia-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652807/
https://www.ncbi.nlm.nih.gov/pubmed/29100416
http://dx.doi.org/10.18632/oncotarget.20767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652807/
https://www.ncbi.nlm.nih.gov/pubmed/29100416
http://dx.doi.org/10.18632/oncotarget.20767

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