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Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity
Autophagy is a cellular bulk degradation pathway implicated in various diseases. Inhibition of autophagy has been regarded as a new therapeutic strategy for cancer treatment, especially in combination with chemotherapy. In our study, we identified two natural compounds, dauricine (DAC) and daurisoli...
Autores principales: | Wu, Ming-Yue, Wang, Sheng-Fang, Cai, Cui-Zan, Tan, Jie-Qiong, Li, Min, Lu, Jin-Jian, Chen, Xiu-Ping, Wang, Yi-Tao, Zheng, Wei, Lu, Jia-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652807/ https://www.ncbi.nlm.nih.gov/pubmed/29100416 http://dx.doi.org/10.18632/oncotarget.20767 |
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