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Meta-analysis of the mutational status of circulation tumor cells and paired primary tumor tissues from colorectal cancer patients

As predictive markers for anti-EGFR therapy, KRAS and BRAF mutations are routinely detected in primary and metastatic colorectal cancer (CRC) cells, but seldom in circulating tumor cells (CTCs). Detecting mutations in CTCs could help explain mutational differences between tumor cells at local sites...

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Detalles Bibliográficos
Autores principales: Liu, Yong, Meucci, Stefano, Sheng, Liming, Keilholz, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652825/
https://www.ncbi.nlm.nih.gov/pubmed/29100436
http://dx.doi.org/10.18632/oncotarget.18272