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Meta-analysis of the mutational status of circulation tumor cells and paired primary tumor tissues from colorectal cancer patients
As predictive markers for anti-EGFR therapy, KRAS and BRAF mutations are routinely detected in primary and metastatic colorectal cancer (CRC) cells, but seldom in circulating tumor cells (CTCs). Detecting mutations in CTCs could help explain mutational differences between tumor cells at local sites...
Autores principales: | Liu, Yong, Meucci, Stefano, Sheng, Liming, Keilholz, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652825/ https://www.ncbi.nlm.nih.gov/pubmed/29100436 http://dx.doi.org/10.18632/oncotarget.18272 |
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