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Chromosomal instability and acquired drug resistance in multiple myeloma

Chromosomal instability (CIN) is an important hallmark of human cancer. CIN not only contributes to all stages of tumor development (initiation, promotion and progression) but also drives, in large measure, the acquisition of drug resistance by cancer cells. Although CIN is a cornerstone of the comp...

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Detalles Bibliográficos
Autores principales: Wang, Wang, Zhang, Yi, Chen, Ruini, Tian, Zhidan, Zhai, Yongpin, Janz, Siegfried, Gu, Chunyan, Yang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652852/
https://www.ncbi.nlm.nih.gov/pubmed/29100463
http://dx.doi.org/10.18632/oncotarget.20829