Possible involvement of ROS generation in vorinostat pretreatment induced enhancement of the antibacterial activity of ciprofloxacin

The mechanism underlying ciprofloxacin action involves interference with transcription and replication of bacterial DNA and, thus, the induction of double-strand breaks in DNA. It also involves elevated oxidative stress, which might contribute to bacterial cell death. Vorinostat was shown to induce...

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Detalles Bibliográficos
Autores principales: Masadeh, Majed M, Alzoubi, Karem H, Al-azzam, Sayer I, Al-buhairan, Ahlam M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652917/
https://www.ncbi.nlm.nih.gov/pubmed/29081676
http://dx.doi.org/10.2147/CPAA.S148448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652917/
https://www.ncbi.nlm.nih.gov/pubmed/29081676
http://dx.doi.org/10.2147/CPAA.S148448

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