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Acid ceramidase confers radioresistance to glioblastoma cells

Glioblastoma multiforme (GBM) is the most common primary, intracranial malignancy of the central nervous system. The standard treatment protocol, which involves surgical resection, and concurrent radiation with adjuvant temozolomide (TMZ), still imparts a grim prognosis. Ultimately, all GBMs exhibit...

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Detalles Bibliográficos
Autores principales: Doan, Ninh B., Nguyen, Ha S., Al-Gizawiy, Mona M., Mueller, Wade M., Sabbadini, Roger A., Rand, Scott D., Connelly, Jennifer M., Chitambar, Christopher R., Schmainda, Kathleen M., Mirza, Shama P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652937/
https://www.ncbi.nlm.nih.gov/pubmed/28765947
http://dx.doi.org/10.3892/or.2017.5855