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Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis

Accumulating data show that prolylisomerase (Pin1) is overexpressed in human glioblastoma multiforme (GBM) specimens. Therefore, Pin1 inhibitors should be investigated as a new chemotherapeutic drug that may enhance the clinical management of human gliomas. Recently, juglone, a Pin1 inhibitor, was s...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Liu, Ke, Wang, Xiao-Feng, Sun, Dian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652942/
https://www.ncbi.nlm.nih.gov/pubmed/28791366
http://dx.doi.org/10.3892/or.2017.5878