TP63 mutations are frequent in cutaneous melanoma, support UV etiology, but their role in melanomagenesis is unclear

In contrast to TP53, cancer development is rarely associated with mutations in the TP63 and TP73 genes. Recently, next generation sequencing analysis revealed that TP63 mutations are frequent, specifically in cutaneous melanomas. Cutaneous melanoma represents 4% of skin cancers but it is responsible...

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Detalles Bibliográficos
Autores principales: Monti, Paola, Ghiorzo, Paola, Menichini, Paola, Foggetti, Giorgia, Queirolo, Paola, Izzotti, Alberto, Fronza, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652947/
https://www.ncbi.nlm.nih.gov/pubmed/28849221
http://dx.doi.org/10.3892/or.2017.5903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652947/
https://www.ncbi.nlm.nih.gov/pubmed/28849221
http://dx.doi.org/10.3892/or.2017.5903

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