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Functional Data Analysis Applied to Modeling of Severe Acute Mucositis and Dysphagia Resulting From Head and Neck Radiation Therapy

PURPOSE: Current normal tissue complication probability modeling using logistic regression suffers from bias and high uncertainty in the presence of highly correlated radiation therapy (RT) dose data. This hinders robust estimates of dose-response associations and, hence, optimal normal tissue—spari...

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Detalles Bibliográficos
Autores principales: Dean, Jamie A., Wong, Kee H., Gay, Hiram, Welsh, Liam C., Jones, Ann-Britt, Schick, Ulrike, Oh, Jung Hun, Apte, Aditya, Newbold, Kate L., Bhide, Shreerang A., Harrington, Kevin J., Deasy, Joseph O., Nutting, Christopher M., Gulliford, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653218/
https://www.ncbi.nlm.nih.gov/pubmed/27788955
http://dx.doi.org/10.1016/j.ijrobp.2016.08.013