Functional dichotomy in spinal- vs prefrontal-projecting locus coeruleus modules splits descending noradrenergic analgesia from ascending aversion and anxiety in rats

The locus coeruleus (LC) projects throughout the brain and spinal cord and is the major source of central noradrenaline. It remains unclear whether the LC acts functionally as a single global effector or as discrete modules. Specifically, while spinal-projections from LC neurons can exert analgesic...

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Detalles Bibliográficos
Autores principales: Hirschberg, Stefan, Li, Yong, Randall, Andrew, Kremer, Eric J, Pickering, Anthony E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653237/
https://www.ncbi.nlm.nih.gov/pubmed/29027903
http://dx.doi.org/10.7554/eLife.29808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653237/
https://www.ncbi.nlm.nih.gov/pubmed/29027903
http://dx.doi.org/10.7554/eLife.29808

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