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The complex relationship between oligoclonal bands, lymphocytes in the cerebrospinal fluid, and immunoglobulin G antibodies in multiple sclerosis: Indication of serum contribution

INTRODUCTION: Intrathecal immunoglobulin G (IgG) and oligoclonal bands (OCBs) are the most consistent and characteristic features of Multiple Sclerosis (MS). OCBs in MS are considered products of clonally expanded B cells in the cerebrospinal fluid (CSF), representing the sum of contributions from B...

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Detalles Bibliográficos
Autores principales: Beseler, Cheryl, Vollmer, Timothy, Graner, Michael, Yu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653326/
https://www.ncbi.nlm.nih.gov/pubmed/29059249
http://dx.doi.org/10.1371/journal.pone.0186842