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Human macrophages differentiated in the presence of vitamin D(3) restrict dengue virus infection and innate responses by downregulating mannose receptor expression

BACKGROUND: Severe dengue disease is associated with high viral loads and overproduction of pro-inflammatory cytokines, suggesting impairment in the control of dengue virus (DENV) and the mechanisms that regulate cytokine production. Vitamin D(3) has been described as an important modulator of immun...

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Detalles Bibliográficos
Autores principales: Arboleda Alzate, John F., Rodenhuis-Zybert, Izabela A., Hernández, Juan C., Smit, Jolanda M., Urcuqui-Inchima, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653353/
https://www.ncbi.nlm.nih.gov/pubmed/29020083
http://dx.doi.org/10.1371/journal.pntd.0005904