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Human macrophages differentiated in the presence of vitamin D(3) restrict dengue virus infection and innate responses by downregulating mannose receptor expression
BACKGROUND: Severe dengue disease is associated with high viral loads and overproduction of pro-inflammatory cytokines, suggesting impairment in the control of dengue virus (DENV) and the mechanisms that regulate cytokine production. Vitamin D(3) has been described as an important modulator of immun...
Autores principales: | Arboleda Alzate, John F., Rodenhuis-Zybert, Izabela A., Hernández, Juan C., Smit, Jolanda M., Urcuqui-Inchima, Silvio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653353/ https://www.ncbi.nlm.nih.gov/pubmed/29020083 http://dx.doi.org/10.1371/journal.pntd.0005904 |
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