Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency

BACKGROUND: Sirtuins are NAD(+) dependent deacetylases, which regulate mitochondrial energy metabolism as well as cellular response to stress. The NAD/NADH-system plays a crucial role in oxidative phosphorylation linking sirtuins and the mitochondrial respiratory chain. Furthermore, sirtuins are abl...

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Detalles Bibliográficos
Autores principales: Potthast, Arne Björn, Heuer, Theresa, Warneke, Simone Johanna, Das, Anibh Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653369/
https://www.ncbi.nlm.nih.gov/pubmed/29059204
http://dx.doi.org/10.1371/journal.pone.0186517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653369/
https://www.ncbi.nlm.nih.gov/pubmed/29059204
http://dx.doi.org/10.1371/journal.pone.0186517

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