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Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency
BACKGROUND: Sirtuins are NAD(+) dependent deacetylases, which regulate mitochondrial energy metabolism as well as cellular response to stress. The NAD/NADH-system plays a crucial role in oxidative phosphorylation linking sirtuins and the mitochondrial respiratory chain. Furthermore, sirtuins are abl...
Autores principales: | Potthast, Arne Björn, Heuer, Theresa, Warneke, Simone Johanna, Das, Anibh Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653369/ https://www.ncbi.nlm.nih.gov/pubmed/29059204 http://dx.doi.org/10.1371/journal.pone.0186517 |
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