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Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study

BACKGROUND: Brain homeostasis deteriorates in sepsis, giving rise to a mostly reversible sepsis-associated encephalopathy (SAE). Some survivors experience chronic cognitive dysfunction thought to be caused by permanent brain injury. In this study, we investigated neuroaxonal pathology in sepsis. MET...

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Detalles Bibliográficos
Autores principales: Ehler, Johannes, Barrett, Lucinda K., Taylor, Valerie, Groves, Michael, Scaravilli, Francesco, Wittstock, Matthias, Kolbaske, Stephan, Grossmann, Annette, Henschel, Jörg, Gloger, Martin, Sharshar, Tarek, Chretien, Fabrice, Gray, Francoise, Nöldge-Schomburg, Gabriele, Singer, Mervyn, Sauer, Martin, Petzold, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653470/
https://www.ncbi.nlm.nih.gov/pubmed/29058589
http://dx.doi.org/10.1186/s13054-017-1850-7