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Notch and its oncogenic activity in human malignancies

BACKGROUND: Increasing evidence has demonstrated that Notch signaling is deregulated in human hematological malignancies and solid tumors. This signaling has a protumorigenic effect but may also act as a tumor suppressor. How induction of a single pathway gives rise to the opposite effects in differ...

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Detalles Bibliográficos
Autores principales: Brzozowa-Zasada, Marlena, Piecuch, Adam, Michalski, Marek, Segiet, Oliwia, Kurek, Józef, Harabin-Słowińska, Marzena, Wojnicz, Romuald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653712/
https://www.ncbi.nlm.nih.gov/pubmed/29104587
http://dx.doi.org/10.1007/s10353-017-0491-z