Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex

The formation of paired helical filaments (PHF), which are composed of hyperphosphorylated Tau protein dissociating from microtubules, is one of the pathological hallmarks of Alzheimer’s disease (AD) and other tauopathies. The most important phosphatase that is capable of dephosphorylating Tau at AD...

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Detalles Bibliográficos
Autores principales: Schweiger, Susann, Matthes, Frank, Posey, Karen, Kickstein, Eva, Weber, Stephanie, Hettich, Moritz M., Pfurtscheller, Sandra, Ehninger, Dan, Schneider, Rainer, Krauß, Sybille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653760/
https://www.ncbi.nlm.nih.gov/pubmed/29062069
http://dx.doi.org/10.1038/s41598-017-12974-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653760/
https://www.ncbi.nlm.nih.gov/pubmed/29062069
http://dx.doi.org/10.1038/s41598-017-12974-4

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