Cargando…
Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
The formation of paired helical filaments (PHF), which are composed of hyperphosphorylated Tau protein dissociating from microtubules, is one of the pathological hallmarks of Alzheimer’s disease (AD) and other tauopathies. The most important phosphatase that is capable of dephosphorylating Tau at AD...
Autores principales: | Schweiger, Susann, Matthes, Frank, Posey, Karen, Kickstein, Eva, Weber, Stephanie, Hettich, Moritz M., Pfurtscheller, Sandra, Ehninger, Dan, Schneider, Rainer, Krauß, Sybille |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653760/ https://www.ncbi.nlm.nih.gov/pubmed/29062069 http://dx.doi.org/10.1038/s41598-017-12974-4 |
Ejemplares similares
-
The Anti-Diabetic Drug Metformin Reduces BACE1 Protein Level by Interfering with the MID1 Complex
por: Hettich, Moritz M., et al.
Publicado: (2014) -
Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis
por: Matthes, Frank, et al.
Publicado: (2018) -
A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling
por: Köhler, Andrea, et al.
Publicado: (2014) -
Yersinia Virulence Factor YopM Induces Sustained RSK Activation by Interfering with Dephosphorylation
por: Hentschke, Moritz, et al.
Publicado: (2010) -
Regulation of mRNA Translation by MID1: A Common Mechanism of Expanded CAG Repeat RNAs
por: Griesche, Nadine, et al.
Publicado: (2016)