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Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa

Previously we reported that corneal epithelial barrier function against Pseudomonas aeruginosa was MyD88-dependent. Here, we explored contributions of MyD88-dependent receptors using vital mouse eyes and confocal imaging. Uninjured IL-1R (−/−) or TLR4 (−/−) corneas, but not TLR2 (−/−), TLR5 (−/−), T...

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Detalles Bibliográficos
Autores principales: Metruccio, Matteo M. E., Tam, Connie, Evans, David J., Xie, Anna L., Stern, Michael E., Fleiszig, Suzanne M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653778/
https://www.ncbi.nlm.nih.gov/pubmed/29062042
http://dx.doi.org/10.1038/s41598-017-14243-w