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An engineered vaccine of the Plasmodium vivax Duffy binding protein enhances induction of broadly neutralizing antibodies

Plasmodium vivax invasion into human reticulocytes is a complex process. The Duffy binding protein (DBP) dimerization with its cognate receptor is vital for junction formation in the invasion process. Due to its functional importance, DBP is considered a prime vaccine candidate, but variation in B-c...

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Detalles Bibliográficos
Autores principales: Ntumngia, Francis B., Pires, Camilla V., Barnes, Samantha J., George, Miriam T., Thomson-Luque, Richard, Kano, Flora S., Alves, Jessica R. S., Urusova, Darya, Pereira, Dhelio B., Tolia, Niraj H., King, Christopher L., Carvalho, Luzia H., Adams, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653783/
https://www.ncbi.nlm.nih.gov/pubmed/29062081
http://dx.doi.org/10.1038/s41598-017-13891-2