Regiospecific Synthesis of Ring A Fused Withaferin A Isoxazoline Analogues: Induction of Premature Senescence by W-2b in Proliferating Cancer Cells

Induction of premature senescence represents a novel functional strategy to curb the uncontrolled proliferation of malignant cancer cells. This study unveils the regiospecific synthesis of novel isoxazoline derivatives condensed to ring A of medicinal plant product Withaferin-A. Intriguingly, the ci...

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Detalles Bibliográficos
Autores principales: Rasool, Faheem, Nayak, Debasis, Katoch, Archana, Faheem, Mir Mohd, Yousuf, Syed Khalid, Hussain, Nazar, Belawal, Chetan, Satti, N. K., Goswami, Anindya, Mukherjee, Debaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653814/
https://www.ncbi.nlm.nih.gov/pubmed/29062040
http://dx.doi.org/10.1038/s41598-017-13664-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653814/
https://www.ncbi.nlm.nih.gov/pubmed/29062040
http://dx.doi.org/10.1038/s41598-017-13664-x

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