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DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression

Accumulation of unfolded and potentially toxic proteins in the endoplasmic reticulum (ER) activates a cell stress adaptive response, which involves a reprogramming of general gene expression. ATF4 is a master stress-induced transcription factor that orchestrates gene expression in cells treated with...

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Detalles Bibliográficos
Autores principales: Adjibade, Pauline, Grenier St-Sauveur, Valérie, Bergeman, Jonathan, Huot, Marc-Etienne, Khandjian, Edouard W., Mazroui, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653821/
https://www.ncbi.nlm.nih.gov/pubmed/29062139
http://dx.doi.org/10.1038/s41598-017-14262-7