11β-hydroxysteroid dehydrogenase type 1 has no effect on survival during experimental malaria but affects parasitemia in a parasite strain-specific manner

Malaria is a global disease associated with considerable mortality and morbidity. An appropriately balanced immune response is crucial in determining the outcome of malarial infection. The glucocorticoid (GC) metabolising enzyme, 11β-hydroxysteroid dehydrogenase-1 (11β-HSD1) converts intrinsically i...

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Detalles Bibliográficos
Autores principales: Vandermosten, L., De Geest, C., Knoops, S., Thijs, G., Chapman, K. E., De Bosscher, K., Opdenakker, G., Van den Steen, P. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653823/
https://www.ncbi.nlm.nih.gov/pubmed/29062028
http://dx.doi.org/10.1038/s41598-017-14288-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653823/
https://www.ncbi.nlm.nih.gov/pubmed/29062028
http://dx.doi.org/10.1038/s41598-017-14288-x

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