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Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens

Subunit viral vaccines are typically not as efficient as live attenuated or inactivated vaccines at inducing protective immune responses. This paper describes an alternative ‘biomimetic’ technology; whereby viral antigens were formulated around a polymeric shell in a rationally arranged fashion with...

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Detalles Bibliográficos
Autores principales: Riitho, Victor, Walters, Adam A., Somavarapu, Satyanarayana, Lamp, Benjamin, Rümenapf, Till, Krey, Thomas, Rey, Felix A., Oviedo-Orta, Ernesto, Stewart, Graham R., Locker, Nicolas, Steinbach, Falko, Graham, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653838/
https://www.ncbi.nlm.nih.gov/pubmed/29062078
http://dx.doi.org/10.1038/s41598-017-13915-x