Alpha-1 antitrypsin augmentation therapy decreases miR-199a-5p, miR-598 and miR-320a expression in monocytes via inhibition of NFκB

Alpha-1 antitrypsin (AAT) augmentation therapy involves infusion of plasma-purified AAT to AAT deficient individuals. Whether treatment affects microRNA expression has not been investigated. This study’s objectives were to evaluate the effect of AAT augmentation therapy on altered miRNA expression i...

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Detalles Bibliográficos
Autores principales: Hassan, Tidi, de Santi, Chiara, Mooney, Catherine, McElvaney, Noel G., Greene, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653852/
https://www.ncbi.nlm.nih.gov/pubmed/29062067
http://dx.doi.org/10.1038/s41598-017-14310-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653852/
https://www.ncbi.nlm.nih.gov/pubmed/29062067
http://dx.doi.org/10.1038/s41598-017-14310-2

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