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Targeting of AUF1 to vascular endothelial cells as a novel anti-aging therapy

BACKGROUND: Inhibition of aging of vascular endothelial cells (VECs) may delay aging and prolong life. The goal of this study was to prepare anti-CD31 monoclonal antibody conjugated PEG-modified liposomes containing the AU-rich region connecting factor 1 (AUF1) gene (CD31-PILs-AUF1) and to explore t...

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Detalles Bibliográficos
Autores principales: He, Jian, Jiang, Ya-Feng, Liang, Liu, Wang, Du-Jin, Wei, Wen-Xin, Ji, Pan-Pan, Huang, Yao-Chan, Song, Hui, Lu, Xiao-Ling, Zhao, Yong-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653898/
https://www.ncbi.nlm.nih.gov/pubmed/29089968
http://dx.doi.org/10.11909/j.issn.1671-5411.2017.08.005