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Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD‐L1 (CD274)‐expression: Possible roles of tumour micro environmental factors for CD274 expression

Aberrant PD‐L1 (CD274) expression has been described in different types of tumour and linked to tumour aggressiveness and a poor prognosis. In primary colorectal carcinomas (CRCs), CD274 expression was reported to be associated with mismatch repair (MMR)‐deficiency, BRAF mutation, and “stem‐like” im...

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Detalles Bibliográficos
Autores principales: Inaguma, Shingo, Lasota, Jerzy, Felisiak‐Golabek, Anna, Kowalik, Artur, Wang, Zengfeng, Zieba, Sebastian, Kalisz, Joanna, Ikeda, Hiroshi, Miettinen, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653930/
https://www.ncbi.nlm.nih.gov/pubmed/29085667
http://dx.doi.org/10.1002/cjp2.81