Elevated microRNA-129-5p level ameliorates neuroinflammation and blood-spinal cord barrier damage after ischemia-reperfusion by inhibiting HMGB1 and the TLR3-cytokine pathway

BACKGROUND: Ischemia-reperfusion (IR) affects microRNA (miR) expression and causes substantial inflammation. Multiple roles of the tumor suppressor miR-129-5p in cerebral IR have recently been reported, but its functions in the spinal cord are unclear. Here, we investigated the role of miR-129-5p af...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Qian, Chen, Feng-Shou, Tan, Wen-Fei, Fang, Bo, Zhang, Zai-Li, Ma, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654055/
https://www.ncbi.nlm.nih.gov/pubmed/29061187
http://dx.doi.org/10.1186/s12974-017-0977-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654055/
https://www.ncbi.nlm.nih.gov/pubmed/29061187
http://dx.doi.org/10.1186/s12974-017-0977-4

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