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Editing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome
BACKGROUND: Adenosine to inosine (A-to-I) RNA editing has been shown to be an essential event that plays a significant role in neuronal function, as well as innate immunity, in mammals. It requires a structure that is largely double-stranded for catalysis but little is known about what determines ed...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654063/ https://www.ncbi.nlm.nih.gov/pubmed/29061182 http://dx.doi.org/10.1186/s13059-017-1324-x |