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Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases
The homeostasis of iron is vital to human health, and iron dyshomeostasis can lead to various disorders. Iron homeostasis is maintained by iron regulatory proteins (IRP1 and IRP2) and the iron-responsive element (IRE) signaling pathway. IRPs can bind to RNA stem-loops containing an IRE in the untran...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654065/ https://www.ncbi.nlm.nih.gov/pubmed/29061112 http://dx.doi.org/10.1186/s13024-017-0218-4 |