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Isolation and characterization of three new anti-proliferative Sesquiterpenes from Polygonum barbatum and their mechanism via apoptotic pathway

BACKGROUND: The emergence of chemoresistant cancers and toxicity related to existing chemotherapeutic agents, demand the search for new pharmacophore with enhanced anti-cancer activity and least toxicity. For this purpose, three new sesquiterpenes were isolated from ethyl acetate fraction of the aer...

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Detalles Bibliográficos
Autores principales: Farooq, Umar, Naz, Sadia, Zehra, Binte, Khan, Ajmal, Ali, Syed Abid, Ahmed, Ayaz, Sarwar, Rizwana, Bukhari, Syed Majid, Rauf, Abdur, Ahmad, Izhar, Mabkhot, Yahia Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654143/
https://www.ncbi.nlm.nih.gov/pubmed/29061136
http://dx.doi.org/10.1186/s12885-017-3667-9