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Isolation and characterization of three new anti-proliferative Sesquiterpenes from Polygonum barbatum and their mechanism via apoptotic pathway
BACKGROUND: The emergence of chemoresistant cancers and toxicity related to existing chemotherapeutic agents, demand the search for new pharmacophore with enhanced anti-cancer activity and least toxicity. For this purpose, three new sesquiterpenes were isolated from ethyl acetate fraction of the aer...
Autores principales: | Farooq, Umar, Naz, Sadia, Zehra, Binte, Khan, Ajmal, Ali, Syed Abid, Ahmed, Ayaz, Sarwar, Rizwana, Bukhari, Syed Majid, Rauf, Abdur, Ahmad, Izhar, Mabkhot, Yahia Nasser |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654143/ https://www.ncbi.nlm.nih.gov/pubmed/29061136 http://dx.doi.org/10.1186/s12885-017-3667-9 |
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