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Randomized Phase II Study of Afatinib Plus Simvastatin Versus Afatinib Alone in Previously Treated Patients with Advanced Nonadenocarcinomatous Non-small Cell Lung Cancer

PURPOSE: This phase II study examined whether the addition of simvastatin to afatinib provides a clinical benefit compared with afatinib monotherapy in previously treated patients with nonadenocarcinomatous non-small cell lung cancer (NA-NSCLC). MATERIALS AND METHODS: Patients with advanced NA-NSCLC...

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Detalles Bibliográficos
Autores principales: Lee, Youngjoo, Lee, Ki Hyeong, Lee, Geon Kook, Lee, Soo-Hyun, Lim, Kun Young, Joo, Jungnam, Go, Yun Jung, Lee, Jin Soo, Han, Ji-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654166/
https://www.ncbi.nlm.nih.gov/pubmed/28111428
http://dx.doi.org/10.4143/crt.2016.546