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Error-Prone and Error-Free Translesion DNA Synthesis over Site-Specifically Created DNA Adducts of Aryl Hydrocarbons (3-Nitrobenzanthrone and 4-Aminobiphenyl)

Aryl hydrocarbons such as 3-nitrobenzanthrone (NBA), 4-aminobiphenyl (ABP), acetylaminofluorene (AAF), benzo(a)pyrene (BaP), and 1-nitropyrene (NP) form bulky DNA adducts when absorbed by mammalian cells. These chemicals are metabolically activated to reactive forms in mammalian cells and preferenti...

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Detalles Bibliográficos
Autores principales: Yagi, Takashi, Fujikawa, Yoshihiro, Sawai, Tomoko, Takamura-Enya, Takeji, Ito-Harashima, Sayoko, Kawanishi, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654197/
https://www.ncbi.nlm.nih.gov/pubmed/29071010
http://dx.doi.org/10.5487/TR.2017.33.4.265