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Clonal dominance and transplantation dynamics in hematopoietic stem cell compartments

Hematopoietic stem cells in mammals are known to reside mostly in the bone marrow, but also transitively passage in small numbers in the blood. Experimental findings have suggested that they exist in a dynamic equilibrium, continuously migrating between these two compartments. Here we construct an i...

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Detalles Bibliográficos
Autores principales: Ashcroft, Peter, Manz, Markus G., Bonhoeffer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654265/
https://www.ncbi.nlm.nih.gov/pubmed/28991922
http://dx.doi.org/10.1371/journal.pcbi.1005803