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Clonal dominance and transplantation dynamics in hematopoietic stem cell compartments
Hematopoietic stem cells in mammals are known to reside mostly in the bone marrow, but also transitively passage in small numbers in the blood. Experimental findings have suggested that they exist in a dynamic equilibrium, continuously migrating between these two compartments. Here we construct an i...
Autores principales: | Ashcroft, Peter, Manz, Markus G., Bonhoeffer, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654265/ https://www.ncbi.nlm.nih.gov/pubmed/28991922 http://dx.doi.org/10.1371/journal.pcbi.1005803 |
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