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The transcription fidelity factor GreA impedes DNA break repair

Homologous recombination repairs DNA double-strand breaks and must function even on actively transcribed DNA. Because break repair prevents chromosome loss, the completion of repair is expected to outweigh the transcription of broken templates. Yet, the interplay between DNA break repair and transcr...

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Detalles Bibliográficos
Autores principales: Sivaramakrishnan, Priya, Sepúlveda, Leonardo A., Halliday, Jennifer A., Liu, Jingjing, Núñez, María Angélica Bravo, Golding, Ido, Rosenberg, Susan M., Herman, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654330/
https://www.ncbi.nlm.nih.gov/pubmed/28976965
http://dx.doi.org/10.1038/nature23907