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Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein
The accumulation of cleaved tau fragments in the brain is associated with several tauopathies. For this reason, we recently developed a transgenic mouse that selectively accumulates a C-Terminal 35 kDa human tau fragment (Tau35). These animals develop progressive motor and spatial memory impairment,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654728/ https://www.ncbi.nlm.nih.gov/pubmed/28917666 http://dx.doi.org/10.1016/j.neurobiolaging.2017.07.005 |