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Binding to RNA regulates Set1 function

The Set1 family of histone H3 lysine 4 (H3K4) methyltransferases is highly conserved from yeast to human. Here we show that the Set1 complex (Set1C) directly binds RNA in vitro through the regions that comprise the double RNA recognition motifs (dRRM) and N-SET domain within Set1 and its subunit Spp...

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Detalles Bibliográficos
Autores principales: Luciano, Pierre, Jeon, Jongcheol, El-kaoutari, Abdessamad, Challal, Drice, Bonnet, Amandine, Barucco, Mara, Candelli, Tito, Jourquin, Frederic, Lesage, Pascale, Kim, Jaehoon, Libri, Domenico, Géli, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654745/
https://www.ncbi.nlm.nih.gov/pubmed/29071121
http://dx.doi.org/10.1038/celldisc.2017.40