Hyperlipidemia-induced cholesterol crystal production by endothelial cells promotes atherogenesis

Endothelial cells (EC) play a key role in atherosclerosis. Although EC are in constant contact with low density lipoproteins (LDL), how EC process LDL and whether this influences atherogenesis, is unclear. Here we show that EC take up and metabolize LDL, and when overburdened with intracellular chol...

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Detalles Bibliográficos
Autores principales: Baumer, Yvonne, McCurdy, Sara, Weatherby, Tina M., Mehta, Nehal N., Halbherr, Stefan, Halbherr, Pascal, Yamazaki, Noboru, Boisvert, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654750/
https://www.ncbi.nlm.nih.gov/pubmed/29066718
http://dx.doi.org/10.1038/s41467-017-01186-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654750/
https://www.ncbi.nlm.nih.gov/pubmed/29066718
http://dx.doi.org/10.1038/s41467-017-01186-z

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