Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants

Multi-marker association tests can be more powerful than single-locus analyses because they aggregate the variant information within a gene/region. However, combining the association signals of multiple markers within a gene/region may cause noise due to the inclusion of neutral variants, which usua...

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Detalles Bibliográficos
Autores principales: Lin, Wan-Yu, Chen, Wei J., Liu, Chih-Min, Hwu, Hai-Gwo, McCarroll, Steven A., Glatt, Stephen J., Tsuang, Ming T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654754/
https://www.ncbi.nlm.nih.gov/pubmed/29066733
http://dx.doi.org/10.1038/s41598-017-13177-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654754/
https://www.ncbi.nlm.nih.gov/pubmed/29066733
http://dx.doi.org/10.1038/s41598-017-13177-7

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