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Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants
Multi-marker association tests can be more powerful than single-locus analyses because they aggregate the variant information within a gene/region. However, combining the association signals of multiple markers within a gene/region may cause noise due to the inclusion of neutral variants, which usua...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654754/ https://www.ncbi.nlm.nih.gov/pubmed/29066733 http://dx.doi.org/10.1038/s41598-017-13177-7 |