Cargando…

Comparison of variance estimators for meta-analysis of instrumental variable estimates

Background: Mendelian randomization studies perform instrumental variable (IV) analysis using genetic IVs. Results of individual Mendelian randomization studies can be pooled through meta-analysis. We explored how different variance estimators influence the meta-analysed IV estimate. Methods: Two ve...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, AF, Hingorani, AD, Jefferis, BJ, White, J, Groenwold, RHH, Dudbridge, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654757/
https://www.ncbi.nlm.nih.gov/pubmed/27591262
http://dx.doi.org/10.1093/ije/dyw123